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lüll Atypical antipsychotics: new drugs, new challenges Mathews M; Muzina DJCleve Clin J Med 2007[Aug]; 74 (8): 597-606Compared with the first-generation, or "typical" antipsychotic drugs, second-generation or atypical antipsychotics cause fewer extrapyramidal (motor) problems, but they pose new challenges, as they often contribute to metabolic disturbances such as weight gain, hyperlipidemia, insulin resistance, and type 2 diabetes mellitus. Patients taking atypical antipsychotics should be monitored for glycemic and cardiovascular risk factors and should receive treatment for such problems as they arise.|Antipsychotic Agents/adverse effects/pharmacology/*therapeutic use[MESH]|Benzodiazepines/therapeutic use[MESH]|Clozapine/therapeutic use[MESH]|Diabetes Mellitus/chemically induced[MESH]|Humans[MESH]|Olanzapine[MESH]|Psychotic Disorders/*drug therapy/physiopathology[MESH]|Risk Factors[MESH]|Risperidone/therapeutic use[MESH]|Weight Gain[MESH] |