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lüll Use of antimicrobial catheter lock solutions to prevent catheter-related bacteremia Bleyer AJClin J Am Soc Nephrol 2007[Sep]; 2 (5): 1073-8Catheter-related bacteremia is an important source of morbidity and mortality in hemodialysis patients. A number of well-designed, controlled, prospective trials using antimicrobial catheter lock solutions to prevent catheter-related bacteremia have shown a dramatic, statistically significant decrease in not only infection but also mortality related to catheter-related bacteremia. Despite evidence of significant benefit, these locks are not routinely used in the United States. This review describes the epidemic problem of catheter-related bacteremia, reviews recent clinical trials with antimicrobial catheter lock solutions, and discusses current options and potential indications for catheter lock solutions in the hemodialysis population.|*Renal Dialysis[MESH]|Anti-Bacterial Agents/*administration & dosage[MESH]|Bacteremia/*etiology/*prevention & control[MESH]|Catheterization/*adverse effects[MESH]|Equipment Contamination/*prevention & control[MESH]|Humans[MESH]|Solutions/administration & dosage[MESH] |