Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll Cancer genetics of epigenetic genes Miremadi A; Oestergaard MZ; Pharoah PD; Caldas CHum Mol Genet 2007[Apr]; 16 Spec No 1 (ä): R28-49The cancer epigenome is characterised by specific DNA methylation and chromatin modification patterns. The proteins that mediate these changes are encoded by the epigenetics genes here defined as: DNA methyltransferases (DNMT), methyl-CpG-binding domain (MBD) proteins, histone acetyltransferases (HAT), histone deacetylases (HDAC), histone methyltransferases (HMT) and histone demethylases. We review the evidence that these genes can be targeted by mutations and expression changes in human cancers.|*Epigenesis, Genetic[MESH]|DNA (Cytosine-5-)-Methyltransferases/genetics[MESH]|DNA-Binding Proteins/genetics[MESH]|Genetic Variation[MESH]|Germ-Line Mutation[MESH]|Histone Acetyltransferases/genetics[MESH]|Histone Deacetylases/genetics[MESH]|Histone Methyltransferases[MESH]|Histone-Lysine N-Methyltransferase/genetics[MESH]|Humans[MESH]|Neoplasms/*genetics/metabolism[MESH]|Oxidoreductases, N-Demethylating/genetics[MESH]|Protein Methyltransferases[MESH] |