Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll Regulatory T cells in health and disease Rouse BTJ Intern Med 2007[Jul]; 262 (1): 78-95The healthy host does not normally develop tissue destructive autoimmunity in part because of the presence of natural regulatory T cells. These cells are best identified by their expression of a unique transcription factor forkhead box transcription factor (Foxp3) that controls their regulatory function. Several other types of regulatory T cells also occur most of which are induced in response to antigen stimulation. Some of these express the Foxp3 transcription factor but many do not. The role of natural T-regulatory cells as well as induceable regulatory cells in autoimmunity, cancer, allergy and infectious disease is described. The current status of therapeutic approaches that modulate regulatory T-cell responses on the outcome of experimental animal and human disease is also discussed.|Animals[MESH]|Autoimmune Diseases/*immunology/therapy[MESH]|Autoimmunity[MESH]|Disease Models, Animal[MESH]|Forkhead Transcription Factors/analysis[MESH]|Humans[MESH]|Hypersensitivity, Immediate/immunology[MESH]|Immune Tolerance/immunology[MESH]|Infections/immunology[MESH]|Neoplasms/immunology[MESH]|T-Lymphocyte Subsets/immunology[MESH]|T-Lymphocytes, Regulatory/*immunology[MESH] |