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lüll Cognitive characteristics of children with genetic syndromes Simon TJChild Adolesc Psychiatr Clin N Am 2007[Jul]; 16 (3): 599-616This article presents the cognitive profile observed in children with one of several common genetic syndromes associated with "nonverbal learning disorders." It introduces the concept of a cognitive endophenotype to help explain the similar pattern of impairments across the syndromes. It explores the explanation of diverse impairments in higher-order visual, spatial, temporal, numerical, and executive cognitive competencies deriving from origins in more basic attentional and spatial cognitive dysfunctions. The importance of a developmental approach to understanding dysfunction is stressed.|Brain/*physiopathology[MESH]|Child[MESH]|Child Behavior Disorders/epidemiology/*genetics/*physiopathology[MESH]|Cognition Disorders/epidemiology/*genetics/*physiopathology[MESH]|Humans[MESH]|Learning Disabilities/epidemiology/genetics/physiopathology[MESH]|Magnetic Resonance Imaging[MESH]|Mental Disorders/epidemiology/*genetics/*physiopathology[MESH] |