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lüll Resolution of autoimmune polyglandular syndrome-associated keratopathy with keratolimbal stem cell transplantation: case report and historical literature review Shah M; Holland E; Chan CCCornea 2007[Jun]; 26 (5): 632-5PURPOSE: To describe the presentation and treatment of a case of autoimmune polyglandular syndrome type 1 (APS1)-associated keratopathy and to review the associated literature. METHODS: A 23-year-old man with decreased vision secondary to APS1-associated keratopathy was treated with systemic immunosuppression and keratolimbal allograft (KLAL) stem cell transplantation. RESULTS: The patient maintains excellent vision 27 months after KLAL and systemic immunosuppression. CONCLUSIONS: An underlying etiology of APS1-associated keratopathy is stem cell deficiency, which can be treated effectively with KLAL and systemic immunosuppression.|Adult[MESH]|Corneal Diseases/*etiology/*surgery[MESH]|Epithelial Cells/transplantation[MESH]|Humans[MESH]|Immunosuppressive Agents/therapeutic use[MESH]|Limbus Corneae/*cytology[MESH]|Male[MESH]|Polyendocrinopathies, Autoimmune/*complications[MESH]|Stem Cell Transplantation/*methods[MESH]|Stem Cells/physiology[MESH]|Transplantation, Homologous[MESH]|Visual Acuity[MESH] |