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lüll Lupus activity in pregnancy Clowse MERheum Dis Clin North Am 2007[May]; 33 (2): 237-52, vPregnancy in a woman with systemic lupus erythematosus (SLE) can be complicated by both lupus activity and pregnancy mishaps. The majority of recent studies found an increase in lupus activity during pregnancy, perhaps exacerbated by hormonal shifts required to maintain pregnancy. Increased lupus activity, in turn, prompts an elevated risk for poor pregnancy outcomes, including stillbirth, preterm birth, low birth weight, and preeclamspsia. Fortunately, the majority of pregnancies in women with SLE are successful. However, the interaction between pregnancy and SLE activity can lead to complications for both mother and baby.|*Lupus Erythematosus, Systemic/blood/diagnosis/drug therapy/physiopathology[MESH]|*Pregnancy Complications/blood/diagnosis/drug therapy/physiopathology[MESH]|*Pregnancy Outcome[MESH]|*Pregnancy, High-Risk/drug effects/physiology[MESH]|Adult[MESH]|Animals[MESH]|Azathioprine/therapeutic use[MESH]|Female[MESH]|Glucocorticoids/therapeutic use[MESH]|Humans[MESH]|Immunosuppressive Agents/therapeutic use[MESH]|Lupus Nephritis/epidemiology[MESH]|Pre-Eclampsia/epidemiology[MESH]|Pregnancy[MESH]|Premature Birth/epidemiology[MESH] |