Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
free
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
free free
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll Pure red cell aplasia due to parvovirus B19 infection after liver transplantation: a case report and review of the literature Liang TB; Li DL; Yu J; Bai XL; Liang L; Xu SG; Wang WL; Shen Y; Zhang M; Zheng SSWorld J Gastroenterol 2007[Apr]; 13 (13): 2007-10Pure red cell aplasia (PRCA) due to parvovirus B19 (PVB19) infection after solid organ transplantation has been rarely reported and most of the cases were renal transplant recipients. Few have been described after liver transplantation. Moreover, little information on the management of this easily recurring disease is available at present. We describe the first case of a Chinese liver transplant recipient with PVB19-induced PRCA during immunosuppressive therapy. The patient suffered from progressive anemia with the lowest hemoglobin level of 21 g/L. Bone marrow biopsy showed selectively inhibited erythropoiesis with giant pronormoblasts. Detection of PVB19-DNA in serum with quantitative polymerase chain reaction (PCR) revealed a high level of viral load. After 2 courses of intravenous immunoglobulin (IVIG) therapy, bone marrow erythropoiesis recovered with his hemoglobin level increased to 123 g/L. He had a low-level PVB19 load for a 5-mo follow-up period without recurrence of PRCA, and finally the virus was cleared. Our case indicates that clearance of PVB19 by IVIG in transplant recipients might be delayed after recovery of anemia.|*Parvovirus B19, Human/genetics[MESH]|Adult[MESH]|Biopsy[MESH]|Bone Marrow/pathology[MESH]|DNA, Viral/blood[MESH]|Humans[MESH]|Immunoglobulins, Intravenous/therapeutic use[MESH]|Immunosuppressive Agents/adverse effects[MESH]|Liver Transplantation/*adverse effects/methods[MESH]|Male[MESH]|Parvoviridae Infections/*complications/etiology[MESH]|Recurrence[MESH]|Red-Cell Aplasia, Pure/diagnosis/drug therapy/*virology[MESH]|Risk Factors[MESH] |