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The diagnosis, staging, and treatment options for mycosis fungoides Keehn CA; Belongie IP; Shistik G; Fenske NA; Glass LFCancer Control 2007[Apr]; 14 (2): 102-11BACKGROUND: Cutaneous T-cell lymphoma (CTCL) represents a spectrum of diseases composed of malignant T lymphocytes. The most common type is mycosis fungoides (MF). An accurate diagnosis of early MF may be difficult because of the varied clinical and histologic expressions of the disease. METHODS: The authors review the epidemiology, possible risk factors, clinical manifestations, diagnostic techniques, staging, prognosis, and treatment options for MF. RESULTS: The varied and often nonspecific clinical and histologic presentations of MF may delay diagnosis and staging, thus necessitating further studies such as immunophenotyping and T-cell receptor gene rearrangement analysis. CONCLUSIONS: A multidisciplinary approach to the diagnosis, staging, and treatment of MF assists in optimizing outcomes from management of patients with this disease.|Antineoplastic Agents/therapeutic use[MESH]|Humans[MESH]|Mycosis Fungoides/*diagnosis/epidemiology/therapy[MESH]|Neoplasm Staging[MESH]|Phototherapy[MESH]|Prognosis[MESH]|Risk Factors[MESH]|Skin Neoplasms/*diagnosis/drug therapy[MESH] |
