Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
 free
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
 free
 free
 
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve
Pubget Overpricing |  
lüll
Synthesis and function of membrane phosphoinositides in budding yeast, Saccharomyces cerevisiae Strahl T; Thorner JBiochim Biophys Acta 2007[Mar]; 1771 (3): 353-404It is now well appreciated that derivatives of phosphatidylinositol (PtdIns) are key regulators of many cellular processes in eukaryotes. Of particular interest are phosphoinositides (mono- and polyphosphorylated adducts to the inositol ring in PtdIns), which are located at the cytoplasmic face of cellular membranes. Phosphoinositides serve both a structural and a signaling role via their recruitment of proteins that contain phosphoinositide-binding domains. Phosphoinositides also have a role as precursors of several types of second messengers for certain intracellular signaling pathways. Realization of the importance of phosphoinositides has brought increased attention to characterization of the enzymes that regulate their synthesis, interconversion, and turnover. Here we review the current state of our knowledge about the properties and regulation of the ATP-dependent lipid kinases responsible for synthesis of phosphoinositides and also the additional temporal and spatial controls exerted by the phosphatases and a phospholipase that act on phosphoinositides in yeast.|1-Phosphatidylinositol 4-Kinase/metabolism[MESH]|Animals[MESH]|Humans[MESH]|Phosphatidylinositol 3-Kinases/metabolism[MESH]|Phosphatidylinositols/*biosynthesis/physiology[MESH]|Phosphoric Monoester Hydrolases/metabolism[MESH]|Phosphotransferases (Alcohol Group Acceptor)/metabolism[MESH]|Saccharomyces cerevisiae Proteins/metabolism[MESH]|Saccharomyces cerevisiae/enzymology/*metabolism/physiology[MESH] |
