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Nuclear architecture--an island no more Dernburg AF; Misteli TDev Cell 2007[Mar]; 12 (3): 329-34The eukaryotic nucleus has been the neglected child of cell biology. The "International Symposium on Functional Organization of the Nucleus" held in January on Awaji Island, Japan, highlighted recent work on nuclear organization and function. Emerging from this conference was a holistic view in which diverse chemical and physical signals link the nuclear and cytoplasmic compartments of cells.|Active Transport, Cell Nucleus/physiology[MESH]|Animals[MESH]|Cell Compartmentation/physiology[MESH]|Cell Differentiation/genetics[MESH]|Cell Lineage/genetics[MESH]|Cell Nucleus Structures/genetics/*metabolism/*ultrastructure[MESH]|Chromatin/genetics/*metabolism/*ultrastructure[MESH]|Genome/genetics[MESH]|Humans[MESH]|Mutation/genetics[MESH]|Nuclear Proteins/genetics/*metabolism[MESH] |
