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lüll Technological advancements for the detection of and protection against biological and chemical warfare agents Eubanks LM; Dickerson TJ; Janda KDChem Soc Rev 2007[Mar]; 36 (3): 458-70There is a growing need for technological advancements to combat agents of chemical and biological warfare, particularly in the context of the deliberate use of a chemical and/or biological warfare agent by a terrorist organization. In this tutorial review, we describe methods that have been developed both for the specific detection of biological and chemical warfare agents in a field setting, as well as potential therapeutic approaches for treating exposure to these toxic species. In particular, nerve agents are described as a typical chemical warfare agent, and the two potent biothreat agents, anthrax and botulinum neurotoxin, are used as illustrative examples of potent weapons for which countermeasures are urgently needed.|*Chemical Warfare Agents/analysis/chemistry/poisoning[MESH]|Anthrax/microbiology/prevention & control[MESH]|Bacillus anthracis/isolation & purification[MESH]|Biological Warfare/*prevention & control[MESH]|Botulism/microbiology/prevention & control[MESH]|Chemical Warfare/*prevention & control[MESH]|Clostridium botulinum/isolation & purification[MESH]|Decontamination/methods[MESH]|Molecular Structure[MESH]|Poisoning/diagnosis/prevention & control[MESH]|Protective Agents/administration & dosage/therapeutic use[MESH] |