suck pdf from google scholar
unlimited free pdf from europmc17304346    free
PDF from PMC    free
html from PMC    free
PDF vom PMID17304346  :  Publisher
PDF vom PMID17304346
suck pdf from library genesis
English Wikipedia

Nephropedia Template TP (

Twit Text


  • DeepDyve
  • Pubget Overpricing


  • lüll
  • Persistent sodium current and its role in epilepsy
  • Stafstrom CE
  • Epilepsy Curr 2007[Jan]; 7 (1): 15-22
  • Sodium currents are essential for the initiation and propagation of neuronal firing. Alterations of sodium currents can lead to abnormal neuronal activity, such as occurs in epilepsy. The transient voltage-gated sodium current mediates the upstroke of the action potential. A small fraction of sodium current, termed the persistent sodium current (I(NaP)), fails to inactivate significantly, even with prolonged depolarization. I(NaP) is activated in the subthreshold voltage range and is capable of amplifying a neuron's response to synaptic input and enhancing its repetitive firing capability. A burgeoning literature is documenting mutations in sodium channels that underlie human disease, including epilepsy. Some of these mutations lead to altered neuronal excitability by increasing I(NaP). This review focuses on the pathophysiological effects of I(NaP) in epilepsy.
  • ä





  • *{{pmid17304346}}
    *<b>[http://www.kidney.de/mlpefetch.php?search=17304346 Persistent sodium current and its role in epilepsy ]</b> Epilepsy Curr 2007; 7(1) ; 15-22 Stafstrom CE

        *17304346*

    Nephropedia PMID record

    Deutsche Wikipedia - im Artikel

    Hier den unten stehenden Textblock hineinkopieren

    Epilepsy Curr

    15 1.7 2007