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Distinguishing diabetic nephropathy from other causes of glomerulosclerosis: an update Alsaad KO; Herzenberg AMJ Clin Pathol 2007[Jan]; 60 (1): 18-26Diabetic nephropathy is a common cause of end-stage renal disease worldwide. It is characterised by diffuse or nodular glomerulosclerosis, afferent and efferent hyaline arteriolosclerosis, and tubulointerstitial fibrosis and atrophy. Diffuse and nodular diabetic glomerulosclerosis share similar histological features with other clinical conditions. Immunofluorescence and electron microscopy studies, and clinicopathological correlation are essential to differentiate diabetic nephropathy from other conditions that result in diffuse and nodular glomerulosclerosis.|Diabetic Nephropathies/*pathology[MESH]|Diagnosis, Differential[MESH]|Glomerulonephritis/*pathology[MESH]|Humans[MESH]|Kidney Glomerulus/ultrastructure[MESH]|Microscopy, Electron[MESH]|Microscopy, Fluorescence[MESH] |
