:  Publisher English Wikipedia <ref>{{Cite pmid|17106237}}</ref> Nephropedia Template TP ( {{tp|p=17106237|t=UVRAG: a new player in autophagy and tumor cell growth |pdf=|usr=|}} Twit Text UVRAG: a new player in autophagy and tumor cell growth http://www.kidney.de/pget.php?&tw=1&pmid=17106237 DeepDyve Pubget Overpricing

lüll UVRAG: a new player in autophagy and tumor cell growth Liang C; Feng P; Ku B; Oh BH; Jung JU Autophagy 2007[Jan]; 3 (1): 69-71 Autophagy has a well-documented role in the maintenance of homeostasis and the response to stressful environments and it is often deregulated in various human diseases including cancer. The regulation of the Beclin 1-PI3KC3 complex lipid kinase activity is a critical element in the autophagy signaling pathway. Previous studies(1) have demonstrated that Beclin 1-PI3KC3-mediated autophagy is negatively regulated by a proto-oncogene Bcl-2. We have recently identified a novel coiled-coil UVRAG tumor suppressor candidate, which positively engages in Beclin 1-dependent autophagy. UVRAG interacts with Beclin 1, leading to activation of autophagy and thereof inhibition of tumorigenesis. This finding adds a new player to the emerging picture of the autophagy network, under-scoring the importance of the coordinated activity between Bcl-2 and UVRAG in the regulation of Beclin 1-PI3KC3-mediated autophagy and tumor cell control. |Animals[MESH] |Autophagy/*physiology[MESH] |Cell Growth Processes/*physiology[MESH] |Humans[MESH] |Neoplasms/*etiology[MESH] |Tumor Suppressor Proteins/*physiology[MESH]

*{{pmid17106237}}
*<b>[http://www.kidney.de/mlpefetch.php?search=17106237 UVRAG: a new player in autophagy and tumor cell growth ]</b> Autophagy 2007; 3(1) ; 69-71 Liang C; Feng P; Ku B; Oh BH; Jung JU

    *17106237*

Nephropedia PMID record
{{recpmid|pmid=17106237|ti=UVRAG: a new player in autophagy and tumor cell growth |au=Liang C; Feng P; Ku B; Oh BH; Jung JU|so=Autophagy 2007; 3 (1): 69-71|ab=Autophagy has a well-documented role in the maintenance of homeostasis and the response to stressful environments and it is often deregulated in various human diseases including cancer. The regulation of the Beclin 1-PI3KC3 complex lipid kinase activity is a critical element in the autophagy signaling pathway. Previous studies(1) have demonstrated that Beclin 1-PI3KC3-mediated autophagy is negatively regulated by a proto-oncogene Bcl-2. We have recently identified a novel coiled-coil UVRAG tumor suppressor candidate, which positively engages in Beclin 1-dependent autophagy. UVRAG interacts with Beclin 1, leading to activation of autophagy and thereof inhibition of tumorigenesis. This finding adds a new player to the emerging picture of the autophagy network, under-scoring the importance of the coordinated activity between Bcl-2 and UVRAG in the regulation of Beclin 1-PI3KC3-mediated autophagy and tumor cell control.}}
Deutsche Wikipedia - im Artikel
<ref>{{BibPMID|17106237}}</ref>
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{{BibRecord | Autor = Liang C; Feng P; Ku B; Oh BH; Jung JU | Titel = UVRAG: a new player in autophagy and tumor cell growth | Band = 3 | Nummer = 1 | Jahr = 2007 | Monat = Jan | Sprache = eng | DOI = | Seite = 69-71 | PMID = 17106237 | Typ= {{{Typ|}}} | Kommentar = {{{Kommentar|}}} | format = {{{format|}}} | record = {{{record|}}} }}

Autophagy