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The rationale for the daily use of an antimicrobial mouthrinse Barnett MLJ Am Dent Assoc 2006[Nov]; 137 Suppl (ä): 16S-21SBACKGROUND: This article reviews the rationale for incorporating effective antimicrobial mouthrinses into a daily oral hygiene regimen along with mechanical plaque control methods. TYPES OF STUDIES REVIEWED: The author reviewed studies demonstrating the essential etiologic role of a pathogenic dental plaque biofilm in the development of gingivitis, as well as studies indicating that most people fail to maintain a level of mechanical plaque control sufficient to prevent disease. In addition, he did a brief review of studies of oral microbial ecology that identified the oral mucosal tissues as a reservoir of bacteria that colonize tooth surfaces, and he summarized six-month clinical studies of marketed antimicrobial mouthrinse ingredients and products. CONCLUSIONS: There is a twofold rationale for daily use of antimicrobial mouthrinses: first, given the inadequacy of mechanical plaque control by the majority of people, as a component added to oral hygiene regimens for the control and prevention of periodontal diseases; second, as a method of delivering antimicrobial agents to mucosal sites throughout the mouth that harbor pathogenic bacteria capable of recolonizing supragingival and subgingival tooth surfaces, thereby providing a complementary mechanism of plaque control. The efficacy of several mouthrinse ingredients and products is supported by published six-month clinical trials. CLINICAL IMPLICATIONS: The daily use of an effective antiplaque/antigingivitis antimicrobial mouthrinse is well-supported by a scientific rationale and can be a valuable component of oral hygiene regimens.|Clinical Trials as Topic[MESH]|Dental Plaque/complications/*prevention & control[MESH]|Gingivitis/etiology/*prevention & control[MESH]|Humans[MESH]|Mouth Mucosa/microbiology[MESH]|Mouthwashes/*administration & dosage[MESH]|Periodontitis/etiology/*prevention & control[MESH] |
