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lüll Managing the complexity of a dynamic biofilm Thomas JG; Nakaishi LAJ Am Dent Assoc 2006[Nov]; 137 Suppl (ä): 10S-15SBACKGROUND: This article provides an overview of the history of oral microbiology, a discussion of dental plaque as both a microbial community and a biofilm, and a review of the measures available to control the oral microflora. TYPES OF STUDIES REVIEWED: The authors reviewed the literature related to oral microbiology and associated infectious diseases. They also examined articles that detailed the structure and physiology of biofilms, including dental plaque biofilms. CONCLUSIONS: Biofilms cannot be eliminated. The pathogenic nature of the dental plaque biofilm can be diminished in the oral cavity by reducing the bioburden and effectively maintaining a normal oral flora via oral hygiene procedures that include daily toothbrushing, flossing and rinsing with an antimicrobial mouthrinse. An oral hygiene regimen that includes rinsing with an antimicrobial mouthrinse is a practical approach to the prevention and management of periodontal diseases. This strategy may have wider benefits when the link between periodontal disease and certain systemic diseases is considered. CLINICAL IMPLICATIONS: An effective oral hygiene regimen can help control dental plaque biofilm and associated periodontal diseases.|Biofilms/*growth & development[MESH]|Dental Plaque/complications/*therapy[MESH]|Humans[MESH]|Mouth/*microbiology[MESH]|Oral Hygiene[MESH] |