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Myc in model organisms: a view from the flyroom de la Cova C; Johnston LASemin Cancer Biol 2006[Aug]; 16 (4): 303-12The Myc transcription factor regulates fundamental processes in a cell's life: its growth, division, and survival. Myc is conserved throughout metazoan phyla, and its identification in the fruit fly, Drosophila melanogaster has led to new insights in Myc's physiological roles. In this review, we describe recent research on the biology of Myc and its family members in Drosophila, paying particular attention to its role in the control of growth during development.|*Animals, Genetically Modified[MESH]|*Signal Transduction[MESH]|Animals[MESH]|Drosophila Proteins/*physiology[MESH]|Drosophila melanogaster/*physiology[MESH]|Gene Expression Regulation, Developmental[MESH]|Proto-Oncogene Proteins c-myc/*physiology[MESH]|Trans-Activators[MESH] |
