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Gap peptides: A new way to control embryonic patterning?Tour E; McGinnis WCell 2006[Aug]; 126 (3): 448-9Gap genes encode transcription factors involved in the patterning of the head-tail axis of insect embryos. In this issue of Cell, Savard et al. (2006) identify a beetle gap gene, mille-pattes, that encodes an unusual polycistronic transcript predicted to produce four conserved peptides. These results have interesting implications for the control of embryonic patterning in insects.|Animals[MESH]|Body Patterning/*genetics[MESH]|Embryo, Nonmammalian/cytology/*embryology[MESH]|Gene Expression Regulation, Developmental/*genetics[MESH]|Insecta/cytology/*embryology/growth & development[MESH]|Peptides/chemistry/*genetics/metabolism[MESH]|RNA/genetics[MESH]|Transcription Factors/chemistry/genetics/metabolism[MESH]|Transcriptional Activation/genetics[MESH]|ras GTPase-Activating Proteins/chemistry/*genetics/metabolism[MESH] |
