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  • FOXP3 and NFAT: partners in tolerance
  • Rudensky AY; Gavin M; Zheng Y
  • Cell 2006[Jul]; 126 (2): 253-6
  • Regulatory T cells suppress autoimmune responses to self-antigens. Recent studies, including one in this issue of Cell (Wu et al., 2006), suggest that the ability of T cells to choose between launching a productive immune response, functional inactivation, or developing into regulatory T cells depends upon the interplay of the key transcriptional regulators FOXP3 and NFAT.
  • |*Immune Tolerance[MESH]
  • |Amino Acid Sequence[MESH]
  • |Amino Acid Substitution[MESH]
  • |Autoimmunity[MESH]
  • |Base Sequence[MESH]
  • |Biomarkers/metabolism[MESH]
  • |CD24 Antigen/immunology[MESH]
  • |Crystallography, X-Ray[MESH]
  • |Forkhead Transcription Factors/chemistry/genetics/*immunology[MESH]
  • |Gene Expression Regulation/genetics/immunology[MESH]
  • |Genes, Reporter[MESH]
  • |Humans[MESH]
  • |Hydrogen Bonding[MESH]
  • |Interleukin-2/genetics/immunology[MESH]
  • |Jurkat Cells[MESH]
  • |Luciferases/metabolism[MESH]
  • |Lymphocyte Activation[MESH]
  • |Models, Biological[MESH]
  • |Molecular Sequence Data[MESH]
  • |NFATC Transcription Factors/chemistry/genetics/*immunology[MESH]
  • |Protein Structure, Tertiary[MESH]
  • |Receptors, Interleukin-2/immunology[MESH]
  • |Sequence Homology, Amino Acid[MESH]
  • |T-Lymphocytes, Regulatory/immunology[MESH]





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    *<b>[http://www.kidney.de/mlpefetch.php?search=16873058 FOXP3 and NFAT: partners in tolerance ]</b> Cell 2006; 126(2) ; 253-6 Rudensky AY; Gavin M; Zheng Y

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    Cell

    253 2.126 2006