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lüll Acute decompensated heart failure: the cardiorenal syndrome Francis GCleve Clin J Med 2006[Jun]; 73 Suppl 2 (ä): S8-13; discussion S30-3The cardiorenal syndrome is not well understood, and a uniform definition is lacking. Worsening renal function as determined by a decline in creatinine clearance in patients with decompensated heart failure is an identifier of patients with this syndrome. Treatment is a challenge. Diuretic therapy is valuable in treating congestion but may worsen renal function. Patients with decompensated heart failure are often refractory to diuretics, in which case higher doses must be used or alternate methods explored to reduce salt and water.|Acute Disease[MESH]|Disease Progression[MESH]|Diuretics/*therapeutic use[MESH]|Furosemide/*therapeutic use[MESH]|Glomerular Filtration Rate[MESH]|Heart Failure/*complications/drug therapy[MESH]|Humans[MESH]|Prognosis[MESH]|Renal Insufficiency/drug therapy/*etiology[MESH]|Syndrome[MESH] |