Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
 free
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
 free
 free
 
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve
Pubget Overpricing |  
lüll
The boundary vector cell model of place cell firing and spatial memory Barry C; Lever C; Hayman R; Hartley T; Burton S; O'Keefe J; Jeffery K; Burgess NRev Neurosci 2006[]; 17 (1-2): 71-97We review evidence for the boundary vector cell model of the environmental determinants of the firing of hippocampal place cells. Preliminary experimental results are presented concerning the effects of addition or removal of environmental boundaries on place cell firing and evidence that boundary vector cells may exist in the subiculum. We review and update computational simulations predicting the location of human search within a virtual environment of variable geometry, assuming that boundary vector cells provide one of the input representations of location used in mammalian spatial memory. Finally, we extend the model to include experience-dependent modification of connection strengths through a BCM-like learning rule - the size and sign of strength change is influenced by historic activity of the postsynaptic cell. Simulations are compared to experimental data on the firing of place cells under geometrical manipulations to their environment. The relationship between neurophysiological results in rats and spatial behaviour in humans is discussed.|Action Potentials/*physiology[MESH]|Animals[MESH]|Hippocampus/anatomy & histology/*physiology[MESH]|Humans[MESH]|Learning/physiology[MESH]|Memory/*physiology[MESH]|Models, Neurological[MESH]|Neural Pathways/anatomy & histology/*physiology[MESH]|Neuronal Plasticity/physiology[MESH]|Neurons/*physiology[MESH]|Orientation/physiology[MESH]|Rats[MESH]|Space Perception/*physiology[MESH] |
