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lüll Understanding structural brain changes in schizophrenia DeLisi LE; Szulc KU; Bertisch HC; Majcher M; Brown KDialogues Clin Neurosci 2006[]; 8 (1): 71-8Schizophrenia is a chronic progressive disorder that has at its origin structural brain changes in both white and gray matter. It is likely that these changes begin prior to the onset of clinical symptoms in cortical regions, particularly those concerned with language processing. Later, they can be detected by progressive ventricular enlargement. Current magnetic resonance imaging (MRI) technology can provide a valuable tool for detecting early changes in cortical atrophy and anomalous language processing, which may be predictive of who will develop schizophrenia.|Antipsychotic Agents/therapeutic use[MESH]|Brain/drug effects/*pathology/*physiopathology[MESH]|Disease Progression[MESH]|Humans[MESH]|Image Processing, Computer-Assisted/methods[MESH]|Magnetic Resonance Imaging/methods[MESH]|Schizophrenia/drug therapy/*pathology/*physiopathology[MESH] |