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Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss Poirier P; Giles TD; Bray GA; Hong Y; Stern JS; Pi-Sunyer FX; Eckel RHArterioscler Thromb Vasc Biol 2006[May]; 26 (5): 968-76Obesity is becoming a global epidemic in both children and adults, and it is associated with numerous co-morbidities such as cardiovascular diseases (CVD), type 2 diabetes, hypertension, certain cancers, and sleep apnea/sleep-disordered breathing. In fact, is an independent risk factor for CVD and CVD risks have been also documented in obese children, and is associated with reduced life expectancy. A variety of adaptations/alterations in cardiac structure and function occur in the individual as adipose tissue accumulates in excess amount. As a whole, overweight/obesity predispose or is associated with numerous cardiac complications such as coronary heart disease, heart failure, and sudden death through its impact on the cardiovascular system.|*Weight Loss[MESH]|Arrhythmias, Cardiac/etiology[MESH]|Cardiovascular Diseases/*etiology/prevention & control[MESH]|Coronary Disease/etiology[MESH]|Echocardiography[MESH]|Electrocardiography[MESH]|Health Services[MESH]|Heart Failure/etiology[MESH]|Humans[MESH]|Hypertension/etiology[MESH]|Obesity/*complications[MESH]|Pulmonary Embolism/etiology[MESH]|Risk Factors[MESH]|Venous Insufficiency/etiology[MESH]|Venous Thrombosis/etiology[MESH] |
