Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll TRAF3: a new regulator of type I interferons Saha SK; Cheng GCell Cycle 2006[Apr]; 5 (8): 804-7Type I interferons are a major and essential component of the mammalian antiviral response. While many cell types produce type I interferons following viral infection, how cells detect the virus has remained a mystery for many years. Recently, multiple genome-encoded viral recognition receptors have been identified. Interestingly, all of the major viral recognition pathways characterized thus far require TRAF3 to initiate type I interferon production. In this review, we comment on the mechanistic and biological implications for the new role of TRAF3 in innate antiviral immunity.|*Gene Expression Regulation[MESH]|*Immunity, Innate[MESH]|Adaptor Proteins, Signal Transducing/metabolism[MESH]|Animals[MESH]|Genome[MESH]|Humans[MESH]|Interferon Type I/*physiology[MESH]|Mice[MESH]|Models, Biological[MESH]|Myeloid Differentiation Factor 88[MESH]|TNF Receptor-Associated Factor 3/metabolism/*physiology[MESH]|Toll-Like Receptors/metabolism[MESH]|Virus Diseases/*immunology[MESH] |