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Chemical and electric transmission in the carotid body chemoreceptor complex Eyzaguirre CBiol Res 2005[]; 38 (4): 341-5Carotid body chemoreceptors are complex secondary receptors. There are chemical and electric connections between glomus cells (GC/GC) and between glomus cells and carotid nerve endings (GC/NE). Chemical secretion of glomus cells is accompanied by GC/GC uncoupling. Chemical GC/NE transmission is facilitated by concomitant electric coupling. Chronic hypoxia reduces GC/GC coupling but increases G/NE coupling. Therefore, carotid body chemoreceptors use chemical and electric transmission mechanisms to trigger and change the sensory discharge in the carotid nerve.|Animals[MESH]|Carotid Body/cytology/*physiology[MESH]|Chemoreceptor Cells/*physiology[MESH]|Humans[MESH]|Nerve Endings/physiology[MESH]|Neurotransmitter Agents/*physiology[MESH]|Synaptic Transmission/*physiology[MESH] |
