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Aldosterone receptor antagonists for heart failure: current status, future indications Pitt B; Rajagopalan SCleve Clin J Med 2006[Mar]; 73 (3): 257-60, 264-8Many patients with heart failure should receive an aldosterone receptor antagonist, ie, either spironolactone (Aldactone) or the newer agent eplerenone (Inspra)--in addition to an angiotensin-converting enzyme (ACE) inhibitor or an angiotensin II receptor blocker (ARB) or both, and a beta-blocker. We review the evidence and indications.|*Mineralocorticoid Receptor Antagonists/*therapeutic use[MESH]|Angiotensin-Converting Enzyme Inhibitors/therapeutic use[MESH]|Eplerenone[MESH]|Forecasting[MESH]|Heart Failure/*drug therapy[MESH]|Humans[MESH]|Practice Guidelines as Topic[MESH]|Randomized Controlled Trials as Topic[MESH]|Risk Factors[MESH]|Spironolactone/analogs & derivatives/therapeutic use[MESH] |
