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lüll Safety of statins: effects on muscle and the liver Vasudevan AR; Hamirani YS; Jones PHCleve Clin J Med 2005[Nov]; 72 (11): 990-3, 996-1001Although statin drugs can have adverse effects on muscles and the liver, these effects are uncommon. Caution is warranted in patients at higher risk, ie, those who are elderly, frail, or small; have multisystem disease; are receiving immunosuppressive drugs or other medications that interact with statins; or are receiving higher doses of a statin.|Alanine Transaminase/blood[MESH]|Animals[MESH]|Aspartate Aminotransferases/blood[MESH]|C-Reactive Protein/metabolism[MESH]|Chemical and Drug Induced Liver Injury[MESH]|Humans[MESH]|Hydroxymethylglutaryl-CoA Reductase Inhibitors/*adverse effects/therapeutic use[MESH]|Hypercholesterolemia/drug therapy[MESH]|Liver Diseases/enzymology[MESH]|Liver/*drug effects/enzymology[MESH]|Lovastatin/*adverse effects/therapeutic use[MESH]|Muscle, Skeletal/*drug effects/enzymology[MESH]|Rhabdomyolysis/blood/chemically induced[MESH] |