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lüll New developments in topical sequential therapy for psoriasis Koo JYSkin Therapy Lett 2005[Nov]; 10 (9): 1-4Topical agents for the treatment of psoriasis are indicated for patients whose affected area is less then 10% of their skin. However, for long-term use, their effectiveness can be limited. Topical sequential therapy involves the application of a class I corticosteroid and calcipotriene in three different phases: the clearance phase, the transition phase and the maintenance phase. It is an accepted and widely practiced technique that provides a balance between maximizing efficacy and minimizing side-effects thus offering patients rapid clearance of their psoriatic lesions and long-term maintenance of remission.|Administration, Topical[MESH]|Adrenal Cortex Hormones/therapeutic use[MESH]|Calcitriol/*analogs & derivatives/therapeutic use[MESH]|Dermatologic Agents/*therapeutic use[MESH]|Drug Therapy, Combination[MESH]|Humans[MESH]|Psoriasis/*drug therapy[MESH] |