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lüll Delirium associated with baclofen withdrawal: a review of common presentations and management strategies Leo RJ; Baer DPsychosomatics 2005[Nov]; 46 (6): 503-7The authors reviewed 23 published cases of psychiatric symptoms in association with baclofen withdrawal. Delirium, and not other functional psychiatric conditions, arose secondarily from abrupt baclofen cessation. Vulnerability to baclofen-withdrawal delirium appeared to be greater in individuals who received chronic baclofen therapy. Baclofen-withdrawal delirium can be difficult to distinguish from delirium of other etiologies, and unrecognized and inadequately treated baclofen-withdrawal delirium is associated with significant morbidity and mortality. Complete resolution of delirium symptoms was possible with reinstatement of baclofen. The clinical management of patients experiencing baclofen-withdrawal delirium includes supportive interventions to reduce complications of delirium until symptoms resolve.|Baclofen/*adverse effects[MESH]|Delirium/*chemically induced/diagnosis/therapy[MESH]|Humans[MESH]|Muscle Relaxants, Central/*adverse effects[MESH]|Substance Withdrawal Syndrome/*etiology[MESH] |