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  lüll Epidemiology, treatment, and prevention of community-acquired  methicillin-resistant Staphylococcus aureus infections Kowalski TJ; Berbari EF; Osmon DRMayo Clin Proc  2005[Sep]; 80 (9): 1201-7; quiz 1208Since first described In 1961, methicillin-resistant Staphylococcus aureus (MRSA)  has become a common nosocomial pathogen. Substantial increases in MRSA infections  among nonhospitalized patients are being reported. Methicillin-resistant S.  aureus is the most common isolate from skin and soft tissue infections in  selected centers in the United States. Community-acquired MRSA strains differ  from nosocomial strains in clinically relevant ways, such as in their propensity  to cause skin and soft tissue infection and severe necrotizing pneumonia.  Clinicians in numerous specialties, particularly primary care physicians, will  likely evaluate patients presentIng with community-acquired MRSA and should  become familiar with the epidemiology and clinical characteristics of and  evolving therapeutic and preventive strategies for this infection.|*Methicillin Resistance[MESH]|Community-Acquired Infections/diagnosis/epidemiology/therapy[MESH]|Humans[MESH]|Staphylococcal Infections/*diagnosis/epidemiology/*therapy[MESH] |