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lüll Immune regulation of gammadelta T cell responses in mycobacterial infections Chen ZWClin Immunol 2005[Sep]; 116 (3): 202-7Antigen-specific gammadelta T cells may play a role in anti-mycobacterial immunity. Studies done in humans and animal models have demonstrated complex patterns of gammadelta T cell immune responses during early mycobacterial infections and chronic tuberculosis. Recent studies have also shown a clinical correlation between major recall expansion of antigen-specific gammadelta T cells and immunity against fatal early mycobacterial diseases. Multiple host and microbial factors can regulate diverse immune responses of phosphoantigen-specific gammadelta T cells during mycobacterial infections.|Animals[MESH]|Antigens, Bacterial[MESH]|Humans[MESH]|Immunologic Memory[MESH]|Lymphocyte Activation[MESH]|Mycobacterium Infections/*immunology[MESH]|Mycobacterium/immunology[MESH]|Phenotype[MESH]|Receptors, Antigen, T-Cell, gamma-delta/*metabolism[MESH]|T-Lymphocyte Subsets/*immunology[MESH]|T-Lymphocytes, Helper-Inducer/immunology[MESH]|Tuberculosis/immunology[MESH] |