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lüll Pharmacology of antiretroviral drugs Hoetelmans RMAntivir Ther 1999[]; 4 Suppl 3 (ä): 29-41In this paper, an overview of the pharmacokinetics of currently available antiretroviral drugs is provided. Included in this article are the agents zidovudine, stavudine, zalcitabine, lamivudine, didanosine, abacavir, nevirapine, delavirdine, efavirenz, saquinavir, indinavir, ritonavir and nelfinavir. Key pharmacokinetic parameters, drug penetration in body compartments and drug interactions are discussed for each agent.|Anti-HIV Agents/administration & dosage/chemistry/metabolism/*pharmacokinetics[MESH]|Cerebrospinal Fluid/metabolism[MESH]|Drug Interactions[MESH]|HIV Infections/drug therapy[MESH]|HIV Protease Inhibitors/administration & dosage/chemistry/metabolism/*pharmacokinetics[MESH]|Humans[MESH]|Reverse Transcriptase Inhibitors/administration & dosage/chemistry/metabolism/*pharmacokinetics[MESH] |