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lüll Can mupirocin prevent methicillin-resistant Staphylococcus aureus infections?Wertheim HF; Vos MCCrit Care 2005[Jun]; 9 (3): 257-8In a retrospective study, Dr Muller and colleagues have assessed the efficacy of mupirocin nasal ointment alongside hygienic measures in methicillin-resistant Staphylococcus aureus (MRSA)-positive patients admitted to the intensive care unit (ICU). Their findings, which suggest that intranasal mupirocin can prevent ICU-related MRSA infections, need confirmation in a well-designed clinical trial. In general: early identification, isolation and treatment of all MRSA carriers, including health care workers, and disinfection of contaminated environments, are the main 'ingredients' of an effective MRSA 'search and destroy' program.|*Methicillin Resistance[MESH]|Administration, Intranasal[MESH]|Anti-Bacterial Agents/administration & dosage/*therapeutic use[MESH]|Cross Infection/*prevention & control[MESH]|Humans[MESH]|Intensive Care Units[MESH]|Mupirocin/administration & dosage/*therapeutic use[MESH]|Staphylococcal Infections/*prevention & control[MESH] |