Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll The pathophysiology of acute graft-versus-host disease Jaksch M; Mattsson JScand J Immunol 2005[May]; 61 (5): 398-409Despite improvements in allogeneic stem cell transplantation, acute graft-versus-host disease (GVHD) remains a significant problem after transplantation, and it is still a major cause of post-transplant mortality. Disease progression is characterized by the differentiation of alloreactive T cells to effector cells leading to tissue damage, recruitment of additional inflammatory cell populations and further cytokine dysregulation. To make the complex process of acute GVHD more explicit, the pathophysiology of acute GVHD is often divided into three different phases. This review summarizes the mechanisms involved in the three phases of acute GVHD.|*Stem Cell Transplantation[MESH]|Acute Disease[MESH]|Animals[MESH]|Cytokines/biosynthesis[MESH]|Cytotoxicity, Immunologic[MESH]|Graft vs Host Disease/immunology/*physiopathology/prevention & control[MESH]|Humans[MESH]|Leukemia/immunology/therapy[MESH]|Lymphocyte Activation[MESH]|T-Lymphocytes/immunology[MESH] |