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Cardiolipin in energy transducing membranes Mileykovskaya E; Zhang M; Dowhan WBiochemistry (Mosc) 2005[Feb]; 70 (2): 154-8Cardiolipin is a phospholipid located exclusively in energy transducing membranes such as the bacterial cytoplasmic membrane and the inner membrane of mitochondria. It plays both a structural and a functional role in many multimeric complexes associated with these membranes. The role of cardiolipin in higher order organization of components of the mitochondrial respiratory chain revealed by a combined molecular genetic and biochemical approach is described.|Animals[MESH]|Cardiolipins/metabolism/*physiology[MESH]|Electron Transport[MESH]|Intracellular Membranes/metabolism/*physiology[MESH]|Macromolecular Substances/metabolism[MESH]|Mitochondria/physiology[MESH]|Saccharomyces cerevisiae/chemistry/physiology[MESH] |