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Role of c-Abl in the DNA damage stress response Shaul Y; Ben-Yehoyada MCell Res 2005[Jan]; 15 (1): 33-5c-Abl has been implicated in many cellular processes including differentiation, division, adhesion, death, and stress response. c-Abl is a latent tyrosine kinase that becomes activated in response to numerous extra- and intra-cellular stimuli. Here we briefly review the current knowledge about c-Abl involvement in the DNA-damage stress response and its implication on cell physiology.|*DNA Damage[MESH]|Animals[MESH]|Apoptosis[MESH]|DNA Repair[MESH]|DNA/metabolism[MESH]|Enzyme Activation[MESH]|Humans[MESH]|Protein Conformation[MESH]|Protein-Tyrosine Kinases/metabolism[MESH]|Proto-Oncogene Proteins c-abl/metabolism/*physiology[MESH] |
