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lüll Skin markers of occult spinal dysraphism in children: a review of 54 cases Guggisberg D; Hadj-Rabia S; Viney C; Bodemer C; Brunelle F; Zerah M; Pierre-Kahn A; de Prost Y; Hamel-Teillac DArch Dermatol 2004[Sep]; 140 (9): 1109-15OBJECTIVES: To verify the diagnostic value of lumbosacral midline cutaneous lesions in asymptomatic children to detect occult spinal dysraphism (OSD) and to propose a practical approach for clinical investigations with respect to the type of cutaneous lesions observed. DESIGN: Retrospective study of 54 children referred to the Department of Pediatric Dermatology between 1990 and 1999 for congenital midline lumbosacral cutaneous lesions. SETTING: The private or institutional practices of participating dermatologists and pediatricians. MAIN OUTCOME MEASURES: Evaluation of the diagnostic value of midline cutaneous lesions for the detec-tion of OSD. Association of skin examination findings with spinal anomalies detected by magnetic resonance imaging or ultrasound. RESULTS: Occult spinal dysraphism was detected in 3 of 36 patients with an isolated congenital midline lesion and 11 of 18 patients with a combination of 2 or more different skin lesions. CONCLUSIONS: A combination of 2 or more congenital midline skin lesions is the strongest marker of OSD. Careful dermatologic examination is needed to detect suggestive markers and request a spinal magnetic resonance image, which is the most sensitive radiologic approach to detect an OSD.|Adolescent[MESH]|Child[MESH]|Child, Preschool[MESH]|Female[MESH]|Hemangioma, Capillary/congenital/diagnosis[MESH]|Humans[MESH]|Infant[MESH]|Infant, Newborn[MESH]|Magnetic Resonance Imaging[MESH]|Male[MESH]|Port-Wine Stain/diagnosis[MESH]|Prognosis[MESH]|Retrospective Studies[MESH]|Sensitivity and Specificity[MESH]|Skin Abnormalities/*diagnosis/surgery[MESH]|Spina Bifida Occulta/*diagnosis/surgery[MESH]|Spinal Dysraphism/diagnosis/surgery[MESH]|Treatment Outcome[MESH]|Ultrasonography, Doppler[MESH] |