Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
Warning: file_get_contents(http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=15380091&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 445
 
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve
Pubget Overpricing |  
lüll
The ups and downs of modeling the cell cycle Ingolia NT; Murray AWCurr Biol 2004[Sep]; 14 (18): R771-7We discuss the impact of mathematical modeling on our understanding of the cell cycle. Although existing, detailed models confirm that the known interactions in the cell cycle can produce oscillations and predict behaviors such as hysteresis, they contain many parameters and are poorly constrained by data which are almost all qualitative. Questions about the basic architecture of the oscillator may be more amenable to modeling approaches that ignore molecular details. These include asking how the various elaborations of the basic oscillator affect the robustness of the system and how cells monitor their size and use this information to control the cell cycle.|*Models, Biological[MESH]|Biological Clocks/*physiology[MESH]|Cell Cycle/*physiology[MESH]|Cell Size[MESH]|Signal Transduction/physiology[MESH] |
