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lüll Thoracic manifestations of breast cancer and its therapy Jung JI; Kim HH; Park SH; Song SW; Chung MH; Kim HS; Kim KJ; Ahn MI; Seo SB; Hahn STRadiographics 2004[Sep]; 24 (5): 1269-85Breast cancer is the second most common cause of cancer-related death in women. In most patients, imaging demonstrates thoracic changes resulting from either treatment, complications of treatment, or tumor recurrence or metastasis. The postsurgical imaging appearance of the chest wall depends on the surgical method used (radical mastectomy, modified radical mastectomy, breast-conserving surgery, breast reconstruction). The most common surgery-related complication is seroma. Radiation therapy frequently causes radiation pneumonitis, which occurs approximately 4-12 weeks after the completion of therapy and is characteristically limited to the field of irradiation. Chemotherapy-related complications include cardiotoxicity, pneumonitis, and infection. Ultrasonography and computed tomography are more sensitive than physical examination for detecting local and regional recurrence. The thorax is a common site of metastasis, which may affect the lymph nodes, bone, lung, pleura, or heart and pericardium. Bone metastasis is usually evaluated with bone scintigraphy and may cause spinal cord compression, a serious complication that requires early diagnosis. Intrapulmonary metastasis may manifest as single or multiple pulmonary nodules, airspace pattern metastasis, lymphangitic metastasis, or endobronchial metastasis. Pleural metastasis usually manifests as pleural effusion, with or without a pleural mass. Familiarity with the spectrum of radiologic findings in breast cancer patients allows accurate image interpretation and correct diagnosis.|Adult[MESH]|Aged[MESH]|Antineoplastic Combined Chemotherapy Protocols/adverse effects[MESH]|Artifacts[MESH]|Breast Neoplasms/*complications/drug therapy/radiotherapy/surgery[MESH]|Female[MESH]|Heart Neoplasms/diagnostic imaging/secondary[MESH]|Humans[MESH]|Lung Neoplasms/diagnostic imaging/secondary[MESH]|Lymphatic Metastasis/diagnostic imaging[MESH]|Mammaplasty[MESH]|Mastectomy/adverse effects/methods[MESH]|Middle Aged[MESH]|Neoplasm Recurrence, Local/diagnostic imaging[MESH]|Pleural Effusion, Malignant/diagnostic imaging/etiology[MESH]|Pneumonia/chemically induced/diagnostic imaging[MESH]|Postoperative Complications/diagnostic imaging/etiology[MESH]|Radiation Injuries/diagnostic imaging[MESH]|Radiotherapy/adverse effects[MESH]|Seroma/diagnostic imaging[MESH]|Spinal Cord Compression/diagnostic imaging/etiology[MESH]|Spinal Neoplasms/diagnostic imaging/secondary[MESH]|Thoracic Diseases/*diagnostic imaging/etiology[MESH]|Thoracic Neoplasms/diagnostic imaging/secondary[MESH]|Tomography, X-Ray Computed[MESH] |