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  • Innovations in attention-deficit/hyperactivity disorder pharmacotherapy: long-acting stimulant and nonstimulant treatments
  • Stein MA
  • Am J Manag Care 2004[Jul]; 10 (4 Suppl): S89-98
  • This article reviews innovations in attentiondeficit/hyperactivity disorder (ADHD) pharmacotherapy and describes research on the newer, long-acting stimulant and nonstimulant treatments for ADHD. Results from peer-reviewed articles comparing the efficacy and safety of longer-acting methylphenidate or amphetamine-based stimulants and the nonstimulant atomoxetine are described. Longer-acting stimulants and nonstimulants provide increased clinical utility compared with short-acting stimulants. Efficacy and safety are similar to 2- or 3-times-a-day treatment with short-acting stimulants. Longer-acting stimulants and nonstimulants provide increased convenience and flexibility for treating youth with ADHD and show considerable promise. Direct head-to-head studies are needed to better inform clinical decision making and to identify moderators and mediators of differential response.
  • |*Diffusion of Innovation[MESH]
  • |Adolescent[MESH]
  • |Attention Deficit Disorder with Hyperactivity/*drug therapy[MESH]
  • |Central Nervous System Stimulants/administration & dosage/classification/*therapeutic use[MESH]
  • |Child[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Treatment Outcome[MESH]
  • |United States[MESH]





  • *{{pmid15352535}}
    *<b>[http://www.kidney.de/mlpefetch.php?search=15352535 Innovations in attention-deficit/hyperactivity disorder pharmacotherapy: long-acting stimulant and nonstimulant treatments ]</b> Am J Manag Care 2004; 10(4 Suppl) ; S89-98 Stein MA

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    Am J Manag Care

    S89 4 Suppl.10 2004