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Complicated and fatal Strongyloides infection in Canadians: risk factors, diagnosis and management Lim S; Katz K; Krajden S; Fuksa M; Keystone JS; Kain KCCMAJ 2004[Aug]; 171 (5): 479-84Strongyloidiasis, which is caused by the nematode Strongyloides stercoralis, is a common and persistent infection, particularly in developing countries. In the setting of compromised cellular immunity, it can result in fulminant dissemination with case-fatality rates of over 70%. The majority of new Canadian immigrants come from countries where Strongyloides is highly endemic; therefore, the burden of Strongyloides may be underappreciated in Canada. Because early diagnosis and therapy can have a marked impact on disease outcome, screening for this infection should be considered mandatory for patients who have a history of travel or residence in a disease-endemic area and risk factors for disseminated disease (e.g., corticosteroid use and human T-lymphotropic virus type I infection).|Animals[MESH]|Canada/epidemiology[MESH]|Diagnosis, Differential[MESH]|Humans[MESH]|Risk Factors[MESH]|Strongyloides/isolation & purification[MESH]|Strongyloidiasis/*complications/diagnosis/drug therapy/*mortality[MESH] |
