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Adverse drug reactions in the orofacial region Scully C; Bagan JVCrit Rev Oral Biol Med 2004[Jul]; 15 (4): 221-39A wide spectrum of drugs can sometimes give rise to numerous adverse orofacial manifestations, particularly dry mouth, taste disturbances, oral mucosal ulceration, and/or gingival swelling. There are few relevant randomized double-blind controlled studies in this field, and therefore this paper reviews the data from case reports, small series, and non-peer-reviewed reports of adverse drug reactions affecting the orofacial region (available from a MEDLINE search to April, 2003). The more common and significant adverse orofacial consequences of drug therapy are discussed.|*Drug-Related Side Effects and Adverse Reactions[MESH]|Facial Pain/chemically induced[MESH]|Gingiva/*drug effects[MESH]|Humans[MESH]|Mouth Diseases/*chemically induced[MESH]|Mouth Mucosa/*drug effects[MESH]|Taste Disorders/chemically induced[MESH]|Tooth Discoloration/chemically induced[MESH]|Trigeminal Nerve Diseases/chemically induced[MESH] |
