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lüll The potential for Toll-like receptors to collaborate with other innate immune receptors Mukhopadhyay S; Herre J; Brown GD; Gordon SImmunology 2004[Aug]; 112 (4): 521-30Cells of the innate immune system express a large repertoire of germ-line encoded cell-surface glycoprotein receptors including Toll-like receptors (TLRs). TLRs recognize conserved motifs on microbes and induce inflammatory signals. Evidence suggests that individual members of the TLR family or other non-TLR surface antigens either physically or functionally interact with each other and cumulative effects of these interactions instruct the nature and outcome of the immune response to a particular pathogen.|Humans[MESH]|Lectins, C-Type[MESH]|Membrane Glycoproteins/*metabolism[MESH]|Membrane Proteins/metabolism[MESH]|Nerve Tissue Proteins/metabolism[MESH]|Receptors, Cell Surface/*metabolism[MESH]|Receptors, IgG/metabolism[MESH]|Receptors, Immunologic/*metabolism[MESH]|Receptors, Purinergic P1/metabolism[MESH]|Signal Transduction/immunology[MESH]|Toll-Like Receptors[MESH] |