Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll Hereditary vascular anomalies: new insights into their pathogenesis Tille JC; Pepper MSArterioscler Thromb Vasc Biol 2004[Sep]; 24 (9): 1578-90Increased understanding of the mechanisms of angiogenesis and lymphangiogenesis has provided a glimpse at some of the molecules involved in the pathophysiology of hemangiomas and vascular malformations. This review focuses on recent advances in our understanding of the mechanisms of angiogenesis/lymphangiogenesis and the differentiation of arterial, venous, and lymphatic vessels. We integrate this knowledge with new data obtained from genetic studies in humans, which have revealed a number of heretofore-unsuspected candidates involved in the development of familial vascular anomalies. We present a common infantile vascular tumor, hemangioma, and then focus on hereditary familial vascular and lymphatic malformations. We also summarize transgenic mouse models for some of these malformations. It seems reasonable to believe that novel therapeutic strategies will soon emerge for the treatment of hemangiomas and vascular malformations.|Animals[MESH]|Arteriovenous Malformations/embryology/genetics/pathology[MESH]|Blood Vessels/*abnormalities/embryology[MESH]|Congenital Abnormalities/embryology/genetics[MESH]|Female[MESH]|Growth Substances/genetics/physiology[MESH]|Hemangioma/embryology/genetics/pathology[MESH]|Humans[MESH]|Infant, Newborn[MESH]|Lymphangiogenesis/genetics[MESH]|Lymphatic System/abnormalities/metabolism[MESH]|Lymphedema/classification/genetics[MESH]|Male[MESH]|Mice[MESH]|Mice, Transgenic[MESH]|Neovascularization, Physiologic/genetics[MESH]|Receptors, Growth Factor/genetics/physiology[MESH]|Remission, Spontaneous[MESH] |