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Natural products active against African trypanosomes: a step towards new drugs Hoet S; Opperdoes F; Brun R; Quetin-Leclercq JNat Prod Rep 2004[Jun]; 21 (3): 353-64This review covers compounds with activity on African trypanosomes (mainly Trypanosoma brucei subsp.,T congolense and T vivax) isolated from natural sources and is organized according to the structure of the etabolites (alkaloids, phenolic derivatives, quinones, terpenes and other metabolites). The literature from he mid-1980s up to June 2003 is reviewed and 89 references are cited.|Africa[MESH]|Alkaloids/chemistry/pharmacology[MESH]|Animals[MESH]|Biological Products/chemistry/*pharmacology[MESH]|Molecular Structure[MESH]|Phenols/chemistry/pharmacology[MESH]|Quinones/chemistry/pharmacology[MESH]|Terpenes/chemistry/pharmacology[MESH]|Trypanosoma/*drug effects[MESH] |
