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lüll Poststreptococcal reactive arthritis: what is it and how do we know?Mackie SL; Keat ARheumatology (Oxford) 2004[Aug]; 43 (8): 949-54OBJECTIVE: To find out whether poststreptococcal reactive arthritis (PSRA) is a discrete, homogeneous clinical syndrome. METHOD: Literature review from case reports and case series. RESULTS: One hundred and eighty-eight cases were identified. The age distribution was bimodal, with one peak in childhood and one peak in adulthood. Eighty-three percent of streptococcal isolates were group A. The clinical presentation was heterogeneous but appeared different both from that of acute rheumatic fever (ARF) and from that of HLA B27-associated reactive arthritis. Carditis was rare. CONCLUSIONS: The term PSRA encompasses significant heterogeneity. The link between the arthritis and the streptococcal infection is unproven.|Adolescent[MESH]|Adult[MESH]|Age Distribution[MESH]|Anti-Infective Agents/therapeutic use[MESH]|Arthritis, Reactive/complications/drug therapy/*microbiology[MESH]|Child[MESH]|Child, Preschool[MESH]|Female[MESH]|HLA Antigens/analysis[MESH]|Humans[MESH]|Male[MESH]|Middle Aged[MESH]|Streptococcal Infections/complications/drug therapy/*microbiology[MESH]|Streptococcus pyogenes/isolation & purification[MESH] |