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Appropriate and effective management of rheumatoid arthritis Breedveld FC; Kalden JRAnn Rheum Dis 2004[Jun]; 63 (6): 627-33Early referral (at <3 months) and early DMARD treatment enable the course of RA to be changed. Once the disease has become aggressive it is much harder to treat and improvements will not be as great as they would have been with earlier treatment. The latest strategies and treatments enable remission to be achieved in many more patients than formerly.|Anti-Inflammatory Agents, Non-Steroidal/therapeutic use[MESH]|Antigens, CD[MESH]|Antigens, Differentiation/immunology[MESH]|Antirheumatic Agents/therapeutic use[MESH]|Arthritis, Rheumatoid/*drug therapy/economics[MESH]|CTLA-4 Antigen[MESH]|Humans[MESH]|Methotrexate/therapeutic use[MESH]|Practice Guidelines as Topic[MESH]|Time Factors[MESH]|Treatment Outcome[MESH]|Tumor Necrosis Factor-alpha/antagonists & inhibitors/immunology[MESH] |
