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lüll Regulation of ion channel expression Rosati B; McKinnon DCirc Res 2004[Apr]; 94 (7): 874-83A potentially important mechanism controlling ion channel expression is homeostatic regulation, which can act to maintain a stable electrophysiological phenotype in cardiac myocytes as well as to provide plasticity in response to genetic, pathological, or pharmacological insults. The capabilities and limitations of the homeostatic regulatory mechanisms that contribute to the control of cardiac ion channel expression are the primary topic of this review.|Animals[MESH]|Arrhythmias, Cardiac/physiopathology[MESH]|Feedback, Physiological[MESH]|Forecasting[MESH]|Gene Expression Regulation, Developmental[MESH]|Guinea Pigs[MESH]|Homeostasis[MESH]|Humans[MESH]|Ion Channels/genetics/*physiology[MESH]|Ion Transport/*physiology[MESH]|Mammals/physiology[MESH]|Mice[MESH]|Mice, Knockout[MESH]|Mice, Transgenic[MESH]|Models, Biological[MESH]|Myocytes, Cardiac/*metabolism[MESH]|Rats[MESH] |