Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
 
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve
Pubget Overpricing |  
lüll
Mitochondrial signaling: the retrograde response Butow RA; Avadhani NGMol Cell 2004[Apr]; 14 (1): 1-15Mitochondrial retrograde signaling is a pathway of communication from mitochondria to the nucleus that influences many cellular and organismal activities under both normal and pathophysiological conditions. In yeast it is used as a sensor of mitochondrial dysfunction that initiates readjustments of carbohydrate and nitrogen metabolism. In both yeast and animal cells, retrograde signaling is linked to TOR signaling, but the precise connections are unclear. In mammalian cells, mitochondrial dysfunction sets off signaling cascades through altered Ca(2+) dynamics, which activate factors such as NFkappaB, NFAT, and ATF. Retrograde signaling also induces invasive behavior in otherwise nontumorigenic cells implying a role in tumor progression.|*Intracellular Signaling Peptides and Proteins[MESH]|Aging/physiology[MESH]|Animals[MESH]|Carrier Proteins/metabolism[MESH]|Cell Nucleus/metabolism[MESH]|Gene Expression Regulation[MESH]|Humans[MESH]|Mitochondria/*metabolism[MESH]|Phosphatidylinositol 3-Kinases/metabolism[MESH]|Phosphotransferases (Alcohol Group Acceptor)/metabolism[MESH]|Saccharomyces cerevisiae Proteins/metabolism[MESH]|Saccharomyces cerevisiae/cytology/metabolism[MESH]|Signal Transduction/*physiology[MESH]|Transcription Factors/metabolism[MESH] |
